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K V Toyka Selected Research

Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)

10/2010[Amyotrophic lateral sclerosis: management of bulbar symptoms].
7/2000Injections of botulinum toxin A into the salivary glands improve sialorrhoea in amyotrophic lateral sclerosis.
6/2000A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis.

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K V Toyka Research Topics

Disease

17Multiple Sclerosis
02/2012 - 01/2000
8Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
08/2005 - 02/2000
7Experimental Autoimmune Neuritis
12/2002 - 05/2000
5Autoimmune Diseases (Autoimmune Disease)
10/2005 - 02/2000
4Disease Progression
01/2004 - 02/2000
4Necrosis
01/2003 - 02/2000
4Inflammation (Inflammations)
06/2001 - 04/2000
3Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
10/2010 - 06/2000
3Pain (Aches)
06/2010 - 06/2001
3Myasthenia Gravis
12/2009 - 01/2001
3Guillain-Barre Syndrome
04/2003 - 01/2001
3Polymyositis
02/2002 - 01/2001
3Autoimmune Diseases of the Nervous System
07/2001 - 05/2000
2Stiff-Person Syndrome (Stiff Man Syndrome)
10/2009 - 07/2003
2Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
12/2003 - 09/2000
2Brain Diseases (Brain Disorder)
07/2003 - 06/2000
2Muscle Weakness
04/2003 - 05/2002
2Human Influenza (Influenza)
06/2002 - 04/2001
2Hyperalgesia
09/2001 - 06/2001
2Miller Fisher Syndrome (Fisher Syndrome)
03/2001 - 01/2001
2Demyelinating Diseases (Demyelinating Disease)
01/2001 - 10/2000
1Psoriasis (Pustulosis Palmaris et Plantaris)
02/2012
1Progressive Multifocal Leukoencephalopathy
02/2012
1Small Fiber Neuropathy
06/2010
1Thymoma (Thymic Carcinoma)
12/2009
1Communicable Diseases (Infectious Diseases)
09/2009
1Encephalomyelitis (Myeloencephalitis)
08/2005
1Chronic Progressive Multiple Sclerosis
05/2005
1Neoplasms (Cancer)
01/2004
1Cardiotoxicity
01/2004
1Ocular Motility Disorders (Convergence Insufficiency)
07/2003
1Myotonic Dystrophy (Dystrophia Myotonica)
02/2003
1Fatigue
12/2002
1Tetanus
06/2002
1Ankylosing Spondylitis
02/2002
1Body Weight (Weight, Body)
02/2002
1Ulcerative Colitis
02/2002

Drug/Important Bio-Agent (IBA)

10CytokinesIBA
06/2010 - 02/2000
8Proteins (Proteins, Gene)FDA Link
10/2009 - 09/2000
7AntibodiesIBA
10/2010 - 01/2001
6Messenger RNA (mRNA)IBA
01/2003 - 02/2000
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2001 - 02/2000
5Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
08/2005 - 04/2000
4Immunoglobulin G (IgG)IBA
10/2009 - 01/2001
4Interferon-gamma (Interferon, gamma)IBA
10/2005 - 10/2000
4Mitoxantrone (Novantrone)FDA LinkGeneric
01/2005 - 01/2000
4AntigensIBA
02/2002 - 05/2000
3Neutralizing AntibodiesIBA
02/2012 - 05/2000
3AutoantigensIBA
11/2001 - 02/2000
3MethylprednisoloneFDA LinkGeneric
08/2001 - 07/2000
2AutoantibodiesIBA
10/2010 - 10/2009
2EpitopesIBA
10/2010 - 11/2001
2amphiphysinIBA
10/2009 - 07/2003
2Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
08/2005 - 03/2001
2Interferon beta-1b (Betaseron)FDA Link
05/2005 - 02/2001
2Pharmaceutical PreparationsIBA
01/2005 - 01/2004
2ChemokinesIBA
07/2004 - 10/2000
2Metalloproteases (Metalloproteinases)IBA
01/2004 - 02/2001
2Matrix Metalloproteinase 9 (Gelatinase B)IBA
12/2003 - 02/2001
2Myelin Basic ProteinIBA
01/2003 - 04/2001
2Mycophenolic Acid (Cellcept)FDA LinkGeneric
02/2002 - 01/2001
2Interferon-betaIBA
07/2001 - 02/2001
2Myelin ProteinsIBA
04/2001 - 05/2000
2Interleukin-10 (Interleukin 10)IBA
12/2000 - 04/2000
1Monoclonal AntibodiesIBA
02/2012
1efalizumab (Raptiva)FDA Link
02/2012
1Myelin-Oligodendrocyte GlycoproteinIBA
10/2010
1Interleukin-2 (IL2)IBA
12/2009
1gamma-Aminobutyric Acid (GABA)IBA
10/2009
1anti-amphiphysin autoantibodyIBA
10/2009
1CalciumIBA
10/2009
1Toll-Like Receptors (Toll-Like Receptor)IBA
09/2009
1Serotonin (5 Hydroxytryptamine)IBA
10/2005
1Cell Adhesion MoleculesIBA
08/2005
1Toll-Like Receptor 4IBA
08/2005
1Prednisone (Sone)FDA LinkGeneric
04/2005
1Adrenocorticotropic Hormone (ACTH)FDA Link
04/2005
1Adrenal Cortex Hormones (Corticosteroids)IBA
04/2005
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
07/2004
1AnthracyclinesIBA
01/2004
1Chelating AgentsIBA
01/2004
1IronIBA
01/2004
1PropaneIBA
01/2004
1Dexrazoxane (Zinecard)FDA LinkGeneric
01/2004
1Intravenous Immunoglobulins (IVIG)FDA Link
12/2003
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
04/2003
1CreatineIBA
02/2003
1Interleukin-4 (Interleukin 4)IBA
01/2003
1Nerve Growth Factor (NGF)IBA
01/2003
1Nerve Growth Factors (Neurotrophins)IBA
01/2003
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2003
1InterleukinsIBA
01/2003
1Transforming Growth Factor beta (TGF-beta)IBA
01/2003
1VaccinesIBA
06/2002
1Adenosine Triphosphate (ATP)IBA
05/2002
1Peptides (Polypeptides)IBA
11/2001

Therapy/Procedure

14Therapeutics
10/2010 - 05/2000
5Immunotherapy
11/2004 - 01/2000
1Immunomodulation
01/2006
1Glycemic Control
12/2003